Education-only · Non-medical · Since 2016
Cluster 3

Protocols

Study schedules referenced. This hub organizes the topic into a starting point, core reading, and deeper reference material so mobile readers and search systems can understand the page pathway quickly.

7 articles Updated Oct 16, 2026 Education only
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Get oriented first

Begin with the plain-language framing before reading narrower claims or legal and safety details.

Core context

Read the central articles

Use the core set to understand the topic before moving into edge cases and supporting references.

Scope limits

Education, not instruction

This section does not provide medical, dosing, sourcing, purchasing, or legal advice.

Recommended first read
Microdosing Protocols: Fadiman, Stamets, and Every-Other-Day Schedules Explained

The common microdosing protocols (Fadiman 1/3/1, Stamets stack, every-other-day) and what each actually rests on. Cited sources, no recipes.

Start →
Core articles
Dosing Schedules Compared: 1/3/1, Every-Other-Day, the Nightcap, and Personalized Calendars

How microdosing calendars differ — Fadiman 1/3/1, every-other-day, the Nightcap, personalized — and their trade-offs. Comparing conventions, not ranking by effect.

Updated Jun 9, 2026 11 min read
How Much Is a Microdose of Mushrooms? Grams, Ranges, and Why Weight Misleads

How much a microdose of mushrooms is in grams, why 0.1–0.3 g is a range not a rule, and why dried weight is a poor proxy for psilocybin content. Cited.

Updated Oct 16, 2026 11 min read
The Fadiman Protocol (1/3/1): What It Is and What Actually Documents It

The Fadiman 1/3/1 microdosing schedule — dose day, two rest days, repeat — its tolerance rationale, and why it's the best-documented protocol but not a proven one.

Updated Jun 9, 2026 11 min read
Deeper reference
The Stamets Stack: Lion's Mane, Niacin, and the Gap Between Rationale and Evidence

The Stamets Stack — psilocybin plus Lion's Mane and niacin: its preclinical rationale, the unsupported niacin claim, and the one study that found no added benefit.

Updated Jun 9, 2026 12 min read
Tolerance and Cycling: Why Protocols Build in Rest Days — and What That Reasoning Does and Doesn't Establish

Why microdosing schedules build in rest days: the tolerance rationale from full-dose pharmacology — and why that plausibility isn't demonstrated microdose benefit.

Updated Jun 9, 2026 11 min read
Tracking and Evaluation: Useful for Your Own Decisions, Powerless to Prove Cause

Why a microdosing log helps your own decisions but can't prove the substance caused the change — self-report on a known dose day is where expectation operates.

Updated Jun 9, 2026 11 min read
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